Studies on Taste Thresholds in Normal Man and in Patients with Adrenal Cortical Insufficiency: the Role of Adrenal Cortical Steroids and of Serum Sodium Concentration.

نویسندگان

  • R I Henkin
  • J R Gill
  • F C Bartter
چکیده

Patients with adrenal cortical insufficiency exhibit an increased taste sensitivity for sodium chloride (NaCl) (1). Treatment with carbohydrate-active steroids returns the abnormal threshold to normal levels (1). In a variety of acute and chronic debilitating diseases, a number of them exhibiting major abnormalities of water and electrolyte metabolism, taste threshold for NaCi is comparable to that observed in healthy subjects (1). Taste thresholds for all modalities are decreased in cystic fibrosis, but they do not change after treatment with steroids (2). The present study was designed to examine in detail taste thresholds in adrenal insufficiency and to explore the effect of adrenal cortical hormones on taste.

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 42 5  شماره 

صفحات  -

تاریخ انتشار 1963